Tart Cherry Extract Supports Urate Metabolism and Reduces CRP, Clinical Study Finds

Tart Cherry Extract Supports Urate Metabolism and Reduces CRP, Clinical Study Finds

A clinical study reported that NordicCherry, a tart cherry extract developed, supported healthy urate metabolism and reduced markers of low-grade systemic inflammation in healthy adults.

Researchers observed meaningful improvements in plasma urate levels and C-reactive protein (CRP), two widely recognized biomarkers used in the assessment of cardiometabolic health.

Why Urate and CRP Matter

Elevated CRP levels can occur even in physically active individuals, often due to:

• Exercise-induced muscle stress

• Oxidative stress

• Dietary and sleep variations

• Minor infections

Although temporary fluctuations are normal, persistently elevated inflammatory markers are associated with long-term cardiometabolic risk.

Maintaining healthy urate metabolism is also important, as urate balance plays a role in metabolic and cardiovascular health.

Study Design

The randomized crossover study included 10 healthy male and female participants.

Subjects received:

• 500 mg of NordicCherry daily for four weeks
  or

• A placebo

A 14-day washout period separated the intervention phases.

Venous blood samples were collected:

• At baseline

• Two, four, and eight hours post-ingestion on day one

• Eight hours post-ingestion on day 28

Key Findings

After four weeks of supplementation:

• Plasma urate levels decreased by an average of 37% compared to baseline

• The placebo group showed a slight increase

Additionally:

• C-reactive protein levels were reduced by 23%

• The placebo group experienced a modest increase

Acute (single-dose) intake did not significantly affect CRP or urate levels, suggesting that consistent supplementation is required to observe measurable benefits.

The supplement was well tolerated, with no adverse events reported.

Broader Implications

NordicCherry has previously been positioned as an ingredient supporting muscle strength and exercise recovery. The new findings suggest that its benefits may extend beyond sports nutrition into broader cardiometabolic health support in otherwise healthy adults.

These results may create opportunities for innovative formulations targeting both active lifestyle consumers and individuals seeking long-term metabolic wellness support.